Recurrence of juvenile dermatomyositis 8 years after remission

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Recurrence of juvenile dermatomyositis 8 years after remission

CDASI: Cutaneous Dermatomyositis Area and Severity Index JDM: juvenile dermatomyositis MTX: methotrexate mPSL: methylprednisolone PSL: prednisolone INTRODUCTION Juvenile dermatomyositis (JDM) is a chronic inflammatory disease characterized by typical skin lesions and muscle weakness, which occurs in children and adolescents younger than 16 years. JDM is classified into 3 clinical types accordin...

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The PRINTO provisional definition of remission in juvenile dermatomyositis

Methods 275 patients in active phase of JDM <18 years, median disease duration 7.7 months, were evaluated at baseline and 24 months. Out of 275 patients, all patients (39/ 275) who were off treatment at 24 months were defined as being in clinical remission and were included as the “gold standard” group. A random sample of patients (n=78) who were in an active phase of JDM at baseline and on med...

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Recurrence of anti-GBM disease 8 years after renal transplantation.

Anti-glomerular basement membrane (GBM) disease is a disorder characterized by antibodies against an epitope of type IV collagen found on the GBM. The major clinical sequela is rapidly progressive glomerulonephritis, which may be accompanied by pulmonary haemorrhage (Goodpasture’s syndrome). Glomerulonephritis secondary to anti-GBM disease frequently progresses to end-stage renal disease (ESRD)...

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Juvenile dermatomyositis.

Juvenile dermatomyositis (JDMS) is a chronic inflammatory condition characterized by muscle weakness and a distinctive rash caused by underlying vasculopathy. Long-term complications include subcutaneous and muscular calcification, contractures and in some cases the gradual development of a second connective tissue disease. Early aggressive treatment with systemic immunosuppressants and other a...

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Juvenile dermatomyositis.

The clinical profile of 7 children and their follow-up is described. There was female preponderance with mate to female ratio of 1:6. The median age of onset was 6 years. All the patients had skin rash, muscle weakness and abnormal enzyme profile. Muscle biopsy was performed in 6 and was abnormal in all of them. The electromyogram (EMG) was performed in 6 and was found abnormal in five. All the...

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ژورنال

عنوان ژورنال: JAAD Case Reports

سال: 2017

ISSN: 2352-5126

DOI: 10.1016/j.jdcr.2016.10.003